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active ingredient agent compound
مكون فعال عامل مركب
ingrediente activo agente compuesto
ماده فعال عامل ترکیب
principe actif agent composé
सक्रिय घटक एजेंट संयोजन
ingrediente attivo agente composto
有効成分 成分 化合物
składnik aktywny czynnik związek
ingrediente ativo agente composto
ingredient activ agent compus
активное вещество агент соединение
etkin madde ajan karışım
активний інгредієнт агент сполука
活性成分 成分 化合物

der  Wirkstoff
B2
Estimated CEFR level.
/ˈvɪʁkʃtɔf/

💊 What exactly is a Wirkstoff?

A Wirkstoff (article: der) refers to the substance in a medication, pesticide, or other product that produces the actual, intended effect. It is the biologically active component.

This contrasts with Hilfsstoffe (excipients) or Trägerstoffe (carrier substances), which are responsible for aspects like the form (tablet), taste, or stability, but do not have their own pharmacological effect.

The word is always masculine: der Wirkstoff.

🧐 Grammar in Detail: Declension of 'der Wirkstoff'

The noun "Wirkstoff" is masculine. Here are the declension tables:

Singular
CaseArticleNoun
Nominative (Nom)derWirkstoff
Genitive (Gen)desWirkstoff(e)s
Dative (Dat)demWirkstoff(e)
Accusative (Acc)denWirkstoff
Plural
CaseArticleNoun
NomdieWirkstoffe
GenderWirkstoffe
DatdenWirkstoffen
AccdieWirkstoffe

💡 Example Sentences

  1. Der Wirkstoff in diesem Medikament ist Ibuprofen. (The active ingredient in this medicine is ibuprofen.)
  2. Die Forscher suchen nach neuen Wirkstoffen gegen Krebs. (The researchers are looking for new active substances against cancer.)
  3. Die Konzentration des Wirkstoffs muss genau dosiert werden. (The concentration of the active ingredient must be dosed precisely.)
  4. Manche Menschen reagieren allergisch auf bestimmte Wirkstoffe. (Some people are allergic to certain active ingredients.)

🌐 How is "Wirkstoff" used?

The term "Wirkstoff" is mainly used in the following contexts:

  • Medizin & Pharmazie (Medicine & Pharmacy): To denote the active component in pharmaceuticals (e.g., der Wirkstoff Paracetamol - the active ingredient paracetamol).
  • Chemie & Biologie (Chemistry & Biology): More generally for substances that exhibit a specific biological effect.
  • Landwirtschaft & Pflanzenschutz (Agriculture & Plant Protection): The active substance in pesticides or herbicides.
  • Kosmetik (Cosmetics): Ingredients intended to have a specific effect on skin or hair (e.g., hyaluronic acid as a Wirkstoff).

It's a somewhat technical or scientific term. In everyday language, people often just talk about the medicine or tablet itself, unless they specifically want to emphasize the active component.

🧠 Mnemonics and Memory Aids

Article Mnemonic: Think of 'DER Stoff' (the substance/material) that works ('wirkt'). Many generic terms for materials are masculine in German (der Stoff, der Baustoff, der Rohstoff...). So it's DER Wirkstoff.

Meaning Mnemonic: Imagine the 'Stoff' (substance) doing the 'WORK' (wirken = to work, to have an effect) in the body. It's the active part. Wirk (effect/work) + Stoff (substance) = substance that works/has an effect.

🔄 Synonyms & Antonyms for Wirkstoff

Same Meaning (Synonyms)

  • Aktiver Inhaltsstoff: (Active ingredient) - Very precise, often used by professionals.
  • Wirksubstanz / Aktive Substanz: (Active substance) - Similar to above.
  • Agens: (Agent) - More scientific (e.g., pharmakologisches Agens - pharmacological agent).
  • Prinzip (rare): (Principle) - E.g., das aktive Prinzip - the active principle of a plant.

Opposite Meaning (Antonyms)

  • Hilfsstoff: (Excipient) - Substance without its own effect, used for form, taste, etc. (e.g., filler, binder).
  • Trägerstoff / Vehikel: (Carrier substance / Vehicle) - Substance that transports or dissolves the active ingredient.
  • Placebo: (Placebo) - Sham medication without an active ingredient.
  • Inertstoff: (Inert substance) - A substance that is chemically unreactive or barely reactive.

⚠️ Similar, but Different Terms

  • Rohstoff: (Raw material) - Unprocessed material used to produce something (can be, but isn't necessarily, an active ingredient).
  • Inhaltsstoff: (Ingredient) - Any substance contained in a product (umbrella term for active ingredients and excipients).

😂 A Little Joke

German: Fragt der Arzt den Apotheker: "Haben Sie etwas gegen Kopfschmerzen?" Antwortet der Apotheker: "Nein, aber ich kann Ihnen einen Wirkstoff verkaufen, der sie Ihnen bereitet!"

English Translation: A doctor asks the pharmacist: "Do you have something for headaches?" The pharmacist replies: "No, but I can sell you an active ingredient that will give you one!"

📜 Poem about the Wirkstoff

German:
Im Pillenkern, ganz tief versteckt,
Der Wirkstoff schlummert, unentdeckt.
Er wartet nur auf den Moment,
Wo er im Körper wirkt, dezent.
Mal lindert Schmerz, mal heilt er Wunden,
Hat oft schon Linderung gefunden.
Ein kleiner Stoff, doch groß die Macht,
hat über Krankheit oft gewacht.

English Translation:
In the pill's core, hidden deep inside,
The active ingredient sleeps, yet untried.
It only waits for the right time,
To work subtly within the body's clime.
Sometimes easing pain, sometimes healing sores,
It has often brought relief to many doors.
A small substance, yet its power is vast,
Over illness, its watchful eye is cast.

❓ Riddle Time

German:
Ich bin der Kern in der Arznei,
Bin nicht der Zucker, nicht der Brei.
Ich sorge für den Effekt,
Bin die Substanz, die man bezweckt.

Wer bin ich?

English Translation:
I am the core within the cure,
Not the sugar, nor the puree.
I provide the main effect,
I'm the substance you expect.

What am I?

Solution: Der Wirkstoff (The active ingredient)

🧩 More Tidbits

Word Composition:

The word "Wirkstoff" is a compound noun, composed of:

  • wirken: to work, to act, to have an effect.
  • der Stoff: material, substance.

So, literally: "A substance that works/has an effect".

Related Terms:

  • Die Wirkung: The effect (that the Wirkstoff has).
  • Wirksamkeit: Efficacy, effectiveness (how well the Wirkstoff works).
  • Nebenwirkung: Side effect (an undesired effect of the Wirkstoff).

📝 Summary: is it der, die or das Wirkstoff?

The word "Wirkstoff" is always masculine. The correct article is der Wirkstoff (in the nominative singular).

🤖

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